3015 N Ocean Blvd, Ste C101, Fort Lauderdale, FL 33308
Office hours: Mon–Sat, 9:00 AM–5:00 PM
Crisis: 988 | Emergency: 911
3015 N Ocean Blvd, Ste C101, Fort Lauderdale, FL 33308
Office hours: Mon–Sat, 9:00 AM–5:00 PM
Crisis: 988 | Emergency: 911
Same-day visits are often possible. See us in our Fort Lauderdale office or by video anywhere in Florida. We take Medicare, Medicaid, Tricare and most major insurance plans. Se habla español.
Mental health conditions like major depressive disorder (MDD), bipolar depression, and schizophrenia can be overwhelming, making it difficult to function in daily life. For many patients, traditional antidepressants aren’t always enough. This is where Brexpiprazole (Rexulti), an FDA-approved medication, can make a life-changing difference.
At One Stop Psychiatry, we provide safe, secure, and confidential access to a Brexpiprazole (Rexulti) treatment through licensed Florida-based providers. Whether you’re in Miami, Miramar, Palm Beach Gardens, or anywhere else in Florida, our telehealth platform ensures you can start treatment without a long wait, by video or at our Fort Lauderdale office.
Brexpiprazole, sold under the brand name Rexulti, is a prescription medication approved by the FDA to treat:
Major Depressive Disorder (MDD) as an adjunct therapy
Schizophrenia
Bipolar depression (off-label use in some cases)
Approved in 2015 for adults with depression and schizophrenia.
Often prescribed when standard antidepressants alone don’t provide enough relief.
Used in combination with SSRIs (selective serotonin reuptake inhibitors) or SNRIs (serotonin-norepinephrine reuptake inhibitors).
Unlike standard antidepressants, Brexpiprazole works on both dopamine and serotonin receptors.
Provides mood stabilization while reducing irritability and psychotic symptoms.
Designed to minimize side effects often seen with older antipsychotics.
If you take Brexpiprazole or have questions about it, our psychiatric medication management service includes a review of your current medications, side effects and a follow-up plan with a licensed provider.
Brexpiprazole is a serotonin-dopamine activity modulator (SDAM). This means it helps balance neurotransmitters linked to mood, thinking, and behavior.
Dopamine impacts motivation, pleasure, and reward.
Serotonin regulates mood, sleep, and emotional stability.
When these chemicals are imbalanced, depression and other mental health disorders can worsen.
Enhances the effectiveness of existing antidepressants.
Reduces symptoms of hallucinations, delusions, and disorganized thinking.
Helps patients feel calmer, more balanced, and emotionally stable.
Getting started is simple, and every step happens with a licensed provider.
Call (754) 270-6322 or request a visit online. Our staff check your insurance, send your intake forms and confirm your appointment, either in our Fort Lauderdale office or by video anywhere in Florida.
You’ll go over your symptoms, health history and current medications. Together you’ll decide whether brexpiprazole makes sense for you or whether another option fits better.
If brexpiprazole is a good fit, your prescription goes to the pharmacy you choose. Follow-up visits let your provider check how it’s working, watch for side effects and adjust the plan. Medication is only prescribed when it’s clinically appropriate.
Not every patient needs Brexpiprazole, but it can be highly effective for certain individuals.
For adults who have tried antidepressants with little or no success, Brexpiprazole can provide the additional boost needed to improve mood and function.
Rexulti is FDA-approved for schizophrenia, helping reduce severe symptoms while improving clarity and focus.
Although not FDA-approved for bipolar depression, some providers may prescribe it off-label if clinically appropriate.
Brexpiprazole, sold under the brand name Rexulti, is an FDA-approved medication most often used as an add-on treatment for major depressive disorder (MDD). In addition to depression, it is also approved for schizophrenia and is being studied for its potential benefits in bipolar depression.
For patients struggling with depressive symptoms related to bipolar disorder, some providers may recommend Brexpiprazole when other medications don’t provide enough relief. Because mental health conditions affect each person differently, the decision to use Brexpiprazole should always be made after a thorough evaluation with a qualified provider. Factors such as your overall health, symptom severity, and past treatment history will guide whether Brexpiprazole (Rexulti) is the right option for you.
Studies have shown that Brexpiprazole, when prescribed alongside an antidepressant, can provide meaningful improvements in mood, daily function, and overall quality of life. Many patients who haven’t responded well to antidepressants alone notice better symptom relief when Rexulti is added to their treatment plan.
However, effectiveness varies from person to person. Your medical history, other health conditions, and current medications all play a role in how well Brexpiprazole works for you. For individuals who feel “stuck” after trying multiple antidepressants, Brexpiprazole may provide a new path forward in managing long-term depression.
Like any medication, Brexpiprazole can cause side effects.
Weight gain
Drowsiness or fatigue
Headaches
Upset stomach
Unusual muscle movements or stiffness
Severe mood changes or suicidal thoughts
Signs of high blood sugar or cholesterol changes
Allergic reactions (rash, swelling, difficulty breathing)
Always consult your provider before adjusting dosage or discontinuing medication.
No. Unlike controlled substances, Brexpiprazole has no risk of addiction or dependency.
Some patients may experience weight changes. Your provider will monitor this as part of your treatment.
Yes. It is often prescribed alongside SSRIs or SNRIs for enhanced effectiveness.
Brexpiprazole usually takes 2–6 weeks to show noticeable improvements.
Patients in Florida who begin Brexpiprazole often report:
Enhanced mood stability and fewer depressive episodes.
Better sleep patterns and emotional regulation.
Flexibility in dosing and combination with antidepressants.
Lower risk of side effects compared to older antipsychotics.
When starting Brexpiprazole (Rexulti), your provider will usually begin with a low dose to minimize potential side effects, gradually adjusting it until the right therapeutic level is reached. It’s important to track your symptoms and side effects during this process and share them with your provider. This helps ensure your dosage is tailored to your individual needs.
Brexpiprazole is typically taken once daily, with or without food. For best results, take it at the same time each day to maintain consistency. If you’re ever unsure about instructions, check with your provider to make sure you’re taking your medication safely.
Keep Brexpiprazole at room temperature, away from direct sunlight, heat, or excess moisture. Always store your medication in a secure location and follow the storage instructions provided on your prescription label.
At One Stop Psychiatry, we know that finding the right depression treatment can feel overwhelming. That’s why our Florida-based psychiatrists provide personalized mental health care, ensuring you get the support you need from start to finish.
Here’s what you can expect:
Thorough Assessment – Share your health history, symptoms, and treatment goals with a licensed provider.
Tailored Care Plan – Your psychiatrist will determine if Brexpiprazole is right for you, or recommend other options such as therapy or additional medications.
Ongoing Support – We don’t just provide a prescription—we check in regularly, monitor your progress, and adjust treatment when needed.
Busy schedule? Trouble finding local clinics? With One Stop Psychiatry, you can see a licensed Florida provider online from the comfort of home. After a private telehealth evaluation, your psychiatrist can send a Brexpiprazole prescription directly to your local pharmacy if it’s the right choice for you.
No long wait times. No unnecessary stress. Just safe, confidential, and convenient ADHD and depression treatment online.
Start your Brexpiprazole (Rexulti) treatment today with One Stop Psychiatry and take the next step toward better mental health.
Call to request an appointment: (754) 270-6322
See all medications we manage or learn about medication management at One Stop Psychiatry.
Learn more about schizophrenia treatment and bipolar disorder treatment at One Stop Psychiatry.
We aren’t an emergency service. If you’re thinking about suicide or you’re in crisis, call or text 988. If you or someone else is in immediate danger, call 911.
Medically reviewed by Dr. Andrew C. Rucker, DO, psychiatrist, on October 6, 2026.
Source: MedlinePlus: brexpiprazole (U.S. National Library of Medicine / NIH). This page is general information, not medical advice.
We accept many insurance plans as well as affordable sliding scale cash plans. Please call our office for more information. (754) 270-6322
You can schedule a therapy consultation with our medical professionals on your time, not theirs.
Your care is with our team of physicians, psychiatric nurse practitioners and a physician assistant. Visits are available in English, Spanish, Russian, Urdu and Hindi. Our staff can help you choose someone who's a good fit.
Dr. Andrew C. Rucker, DOPsychiatrist
Dr. Murtaza Ali, DOAddiction specialist and family physician
Dr. Heather Brathwaite, PhD, PMHNP-BCPsychiatric nurse practitioner
Michelle KovalPsychiatric nurse practitioner. Speaks Russian
Neal Fouke, PAPsychiatric physician assistant
Muhammad Nawaz, PMHNP-BCPsychiatric nurse practitioner. Speaks Urdu and HindiTell us how to reach you. Our team calls back the same business day, Monday to Saturday, 9 AM to 5 PM. Your appointment is confirmed once staff call you to set the time and place.
Prefer to talk to someone? Call (754) 270-6322.
3015 N Ocean Blvd, Ste C101, Fort Lauderdale, FL 33308. Phone: (754) 270-6322. Open Monday to Saturday, 9 AM to 5 PM. Video visits are available anywhere in Florida. Directions and parking.
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